After a decade of advocacy from the AMA, the Food and Drug Administration (FDA) this spring finally removed its longstanding restrictions on blood donations from men who have sex with men. Jesse M. Ehrenfeld, MD, MPH, who is the first openly gay person elected as AMA president said that the fact the victory came so recently shows that stigma and discrimination against LGBTQ+ people are still prevalent. The AMA is advocating that the FDA push this policy further by removing similar restrictions regarding corneas, human cells, and other tissue-based products. It is just one of several ways in which the AMA is working to address inequities affecting LGBTQ+ patients. Most recently, the AMA House of Delegates adopted a policy calling for equal access to adoption services for LGBTQ+ families; endorsed efforts to encourage more LGBTQ+ representation in medicine, and reaffirmed its support for dedicated public health and public policy to lower suicides among LGBTQ+ youth. In addition, the AMA and others filed an amicus brief in federal court to protect access to pre-exposure prophylaxis (PrEP) and other preventive care services under the Affordable Care Act. The AMA is working diligently at the state and federal levels to expand access to medical services, reduce stigma in treating patients with unique needs, and break down discriminatory barriers to necessary care.